The Astros' struggles continued in Denver as their potent offense could only muster a second-inning home run by Christian Walker. Starter Mike Burrows was hampered by defensive miscues, including a dropped fly ball that allowed a run to score in the second inning.
Colorado added two more runs in the fourth inning on a two-run homer by Willi Castro and sealed the victory with two runs in the seventh. The Astros will look to salvage the series finale with Cristian Javier on the mound.